–
Introduction The world of genetics has always been a mesmerizing and an enticing field, but nothing appeals more intensely than the subject of nuclear genomes. These undoubtedly play an essential and irrefutable role in shaping life as we perceive it today. The Epicenter of Life – The Nucleus Within the bustling cellular city, the nucleus … Read more
Introduction to the Druggable Genome Mapping the complexities of the human genome may have been a prominent milestone in scientific history, but our understanding remains at the cusp of embryonic development when it pertains to the concept of the druggable genome. This fascinating subject involves identifying genetic elements that have the potential of reacting positively … Read more
Introduction Diving into the fascinating world of genetics, the subject of DNA introns often comes up as an intriguing element with its complex function and role in the grand scheme of genetic coding. As a crucial part of DNA, introns remain mostly in the dark, overshadowed by the famous exons, which carry vital genetic information. … Read more
Introduction to Single Cell DNA Sequencing In the labyrinth of genetics research, a ground-breaking technique known as single cell DNA Sequencing has emerged. This ingenious method serves as a magnifying glass, allowing researchers to scrutinise individual cell’s genetic material. It is an open door into a realm previously masked by the limitations of bulk sequencing. … Read more
Introduction In the extensive panorama of molecular biology, one cannot overlook the pivotal role of the Small Subunit Ribosomal RNA (SSU rRNA). A key component of the protein synthesis machinery, SSU rRNA functions as a structural and functional scaffold within the small subunit of the ribosome. Section 1: SSU rRNA: An Essential Molecular Machine The … Read more
A Dawn in Scientific Research: Full Genome Sequencing The last few decades witnessed the dramatic expansion of knowledge about the human genome. The "book of life" has been unraveled, revealing the secrets of our identity, traits, and predispositions, thanks to the most advanced technique known as full genome sequencing. Genesis of Full Genome Sequencing The … Read more
Introduction The world of genetic analysis and genomics has opened new frontiers in medical science such as whole genome sequencing analysis. This revolutionary technology possesses the capacity to decode and understand the entire genetic makeup of an organism, offering unprecedented insights to researchers and healthcare professionals alike. Part I: The Essence of Whole Genome Sequencing … Read more
Introduction to IMGT/HLA Principally, the International ImMunoGeneTics project/ Human Leukocyte Antigen (IMGT/HLA) database comprises an extensive compendium of the HLA genes’ allelic sequences. Revered as a prodigious scientific breakthrough, the IMGT/HLA database elucidates the genotypic fingerprint of myriad diseases, therefore streamlining the path to high prognosis treatment profiles. The knowledge of HLA genes contributes significantly … Read more
Introduction to RPE65 RPE65 is not your everyday acronym. It stands as a beacon in the field of genetic disorders, shedding light on some previously unexplainable events. In technical terms, RPE65 is a gene found in humans that is usually associated with certain types of hereditary blindness. However, understanding the full scope of this gene … Read more