Introduction The realm of germline genetics has been opening new doors in our understanding of human health, development, and disease. At the frontier of this exciting field lies the germline genome, a concept capable of revolutionizing our perspective on genetic inheritance. Unveiling the Germline Genome In every individual, the germline genome forms an unbroken chain … Read more
Understanding MTHFR Homozygous Mutation As our understanding of our own genetics continues to grow, tests have emerged that reveal more about our inherited health risks. One such test screens for the presence of MTHFR mutations, specifically for the MTHFR homozygous mutation—a term now widely associated with a variety of health issues. MTHFR stands for methylenetetrahydrofolate … Read more
Introduction The advent of RNA sequencing (‘RNA-seq’) technology has revolutionized the horizons of genomic research. RNA-seq utilizes the capabilities of next-generation sequencing (NGS) to examine the quantity and sequences of RNA in a sample. Herein, we aim to guide you through the intricacies of pathway analysis in RNA-seq with clarity and depth. Understanding RNA-seq The … Read more
Introduction The completion of the Human Genome Project marked a monumental milestone in the realm of genomic research. This ambitious venture embarked upon the unravelling of human life’s quintessential blueprint – the DNA. In this detailed analysis, we delve into the intricacies underpinning the project’s successful completion and its lasting implications in the field of … Read more
In the continuous bid to move healthcare forward, the advent of Single-Cell DNA Sequencing has marked a significant leap. The transformative change it brings to the genomic landscape is nothing less than extraordinary. This article aims to bring you an in-depth, detailed exploration of this vital topic. Single-Cell DNA Sequencing: An Overview Single-cell DNA Sequencing, … Read more
Introduction Wilson’s disease, an autosomal recessive disorder, impacts diverse organs in the body, including the eyes. The disease’s manifestation in the eyes is seen in the form of a particular sign known as the ‘Kayser-Fleischer Ring’ or ‘Sunflower Cataract’. Therefore, it is integral that these symptoms are swiftly recognized and adequately addressed by healthcare professionals. … Read more
Introduction As we navigate the forward-thinking era of scientific revolutions, mRNA and Cas9 have stood out as dominant forces in the biotechnological field. These cutting-edge technologies are spearheading vast and unconventional changes in multiple industries. The Essence of mRNA The term mRNA is an abbreviation for messenger ribonucleic Acid, a pivotal element of genetic codes … Read more
Introduction The Alliance for Clinical Trials in Oncology is a transformative entity that has reshaped the landscape of cancer clinical research throughout the world. Operating as a cooperative group, their influence extends to every corner of clinical trials, from the design stage to data analysis and reporting. The Founding of the Alliance for Clinical Trials … Read more
Introduction Decoding the Mysterious Language of Life: DNA and RNA Sequencing Deciphering the complex world of DNA and RNA sequencing engrosses a wide range of modern scientific endeavours, potentially empowering revolutionary advancements in diverse areas like healthcare, forensics, and palaeontology. Immersed in this intricate biological language lie answers to scores of unresolved questions intricately tied … Read more
Section 1: Introducing the FH Gene The world of human genetics is remarkably vast, each part intricately endorsing the phenomenal complexities of life. Within this daunting expanse lies the FH Gene, known scientifically as the Fumarate Hydratase ‘FH’ gene. In the following in-depth discussion, we will unfold the essence of the FH gene, elaborating on … Read more